psoralen - definizione. Che cos'è psoralen
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Cosa (chi) è psoralen - definizione

CHEMICAL COMPOUND
Psoralens
  • Synthesis of psoralen from 6-hydroxycoumaran
  • Structures of angelicin, xanthotoxin, bergapten and nodekenetin
  • Synthesis of psoralen from 6-hydroxycoumaran

psoralen         
['s?:r?l?n]
¦ noun Chemistry any of a group of cyclic compounds present in certain plants, used to treat psoriasis and other skin disorders.
Origin
1930s: from mod. L. Psoralea (former plant genus name), from Gk psoraleos 'itchy' (from psora 'itch') + the suffix -en (cf. -ene).
PUVA therapy         
ULTRAVIOLET LIGHT THERAPY TREATMENT
Puva therapy; PUVA; Psoralen and ultraviolet A therapy; Psoralen plus ultraviolet A; Narrowband UVB therapy; Psoralen and ultraviolet A phototherapy
PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen. The psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA.

Wikipedia

Psoralen

Psoralen (also called psoralene) is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins. It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone. Psoralen occurs naturally in the seeds of Psoralea corylifolia, as well as in the common fig, celery, parsley, West Indian satinwood, and in all citrus fruits. It is widely used in PUVA (psoralen + UVA) treatment for psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma; these applications are typically through the use of medications such as Methoxsalen. Many furanocoumarins are extremely toxic to fish, and some are deposited in streams in Indonesia to catch fish.